Turn challenges into opportunities
Let card nu-lax to help you overcome from over-the-counter (OTC) products to remove the titanium dioxide (TiO2) challenge.Although this seems to be a difficult task, but it's also a by increasing degree of swallowingImprove consumer experienceGreat opportunity, but also to improve the product color, opacity, and stabilityproductivityCreate the opportunity.
The importance of film coating of tablet
For manufacturers,Thin film coating can bring obvious benefits, for example, the protection of the active ingredient is not affected by light, moisture and oxygen, make the tablet more solid, so as to facilitate packaging and processing.
For consumers, comply with the treatment plan is very important.Thin film coating can mask the smell, provide good palatability, effect is remarkable.When a consumer is to identify and link the color of the tablet with the brand, they are better able to recognize and remember the tablets for their treatment, moreover, the surface is smooth and beautiful product is easier to remember, also easier to swallow.
Understand the challenges
TiO2Is an approved for edible pigment,At the same time also is widely used in medicine.As a kind of sunscreen, TiO2Played a role in the tablet coating, can protect active substance is not affected by light, also can add color.
Recently, the European food safety authority (EFSA) announced that E171 (TiO2) was no longer perceived as a safe food additive, EFSA promised as soon as possible from the safe food additive line out.The industry is likely to ban the before the end of 2021.
Despite the ban will affect E171 used in food, but there is no requirement to its removal from the drug product.European self-medication industry association (AESGP) has set up a group E171, direct drug administration (EMA) to interact with Europe, and provide relevant EMA required to use TiO2The application of the scale, whether has the potential of alternative materials and the influence on the replacement.
Want to get similar to TiO2 opacity challenging, it is also a card nu-lax investment in the development of a series of alternative formulations, including extremely excellent whitenessDo not contain titanium dioxide thin film coating system, Inuit Fiji ®, based on the deep understanding of the coating material master, we've been able to develop the same performance, and alternative formula combines visual appeal.
Light stability is a need to know to grasp the key factors.Light degradation of the active ingredient in raw material and pigment fade, change the appearance of the tablets.Card nu-lax experts developed do not contain titanium dioxide coating formula, can make the coating after the tablet directly exposed to the light, according to the reference standard determination of pigment on the spectrophotometer.Containing calcium carbonate to replace titanium dioxide to replace coating performance is best, can provide sunscreen protection and minimize color changes, at the same time improve the stability and shelf life.
Through innovation and change challenges into opportunities
For many OTC brand, this is a great time to improve existing products, never containing titanium dioxide thin film coating is the latest innovation in harvest, so as to lead to better consumer experience.
Time to # 1 - improve the stability of the tablets
Drug exposure in damp environment will lead to the sensitive active pharmaceutical ingredient degradation, serious impact on the stability and efficacy of drugs.Thin film coating can protect sensitive compounds in front of the packaging is not affected by temperature and humidity change, including bulk product storage, transportation or repackage, and so on and so forth.This stage is to improve the inner packing product stability, and ensure the integrity of the product in its use of a time.
The generation of Obama ® amb IIIs the preferred type humidity sensitive drug coating system.To view the latest case studies, learn more aboutMoistureproof film coating on the stability of amoxicillin/clavulanic acid tablets.The results confirmed that the generation of amb Obama II protect the integrity of the humidity sensitive type compound effects far beyond the inner packing.
# 2 - increase productivity
If productivity is the bottleneck of manufacturing, thenRapid flexible thin film coating system, the generation of ® QXIs you don't.
Generation of QX Obama for coating tablet has redefined the new productivity, efficiency and appearance standards.Generation of Obama QX high solid content and low viscosity ingredients can make it in any type of coating equipment and process parameters in any coating under, shortens the time of preparation and the coating surface treatment at the same time provide quality.Through the coating under high solid content (35%), can reduce more than 40% of the coating time.Within the scope of a wide range of process parameters, and the generation of QX extremely flexibility during use, this means that the product is very easy to from a production facility is transferred to another production facilities.
Card nu-lax provides a comprehensive portfolio of products, available at any time, to improve consumer experience.
